Biotinylated Human Mesothelin / MSLN (296-600) Protein, His,Avitag™ (MALS verified)

DESCRIPTION

Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.

DETAILS

Tag: C-10×His & C-Avi
Host: HEK293
Size: 25ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Biotinylated Human Mesothelin (296-600), His,Avitag (MSN-H82E7) is expressed from human 293 cells (HEK293). It contains AA Glu 296 - Thr 600 (Accession # AAH09272.1).
Storage: -20℃
Category: MABSol® Biotin Labeled Proteins
Molecule: Mesothelin
Accession: AAH09272.1
Conjugate: Biotin-labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Glu 296 - Thr 600
Swiss-prot: Q13421-3 (R309P)
Package Size: 25ug*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 37.8 kDa. The protein migrates as 8 kDa and 42-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 0.1 EU per μg
Molecular Weight: 37.8 kDa
Shipping Condition: RT
Species Reactivity: Human
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