HIST1H2BJ/HIST1H2BK/HIST3H2BB Blocking Peptide(C-term)

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 8970
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: H2BC11
Other Names: Histone H2B type 1-J, Histone H2B1, Histone H2Br, H2B/r, HIST1H2BJ, H2BFR
Availability: 2 weeks
Bio Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq].
Bio References: Shi, J., et al. Nature 460(7256):753-757(2009) Benyamin, B., et al. Am. J. Hum. Genet. 84(1):60-65(2009) Kim, S.C., et al. Mol. Cell 23(4):607-618(2006) Beck, H.C., et al. Mol. Cell Proteomics 5(7):1314-1325(2006) Pavri, R., et al. Cell 125(4):703-717(2006)
Other Accession: P57053; Q64524; Q8CGP1; Q2PFX4; O60814; Q2M2T1; P06900; P02281; NP_066402.2
Primary Accession: P06899
Targetspecificity: The synthetic peptide sequence is selected from aa 113-126 of HUMAN HIST1H2BJ