PPP1CB Antibody (C-term) Blocking peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 5500
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: PPP1CB
Other Names: Serine/threonine-protein phosphatase PP1-beta catalytic subunit, PP-1B, PPP1CD, PPP1CB
Availability: 2 weeks
Bio Background: The protein encoded by this gene is one of the threecatalytic subunits of protein phosphatase 1 (PP1). PP1 is aserine/threonine specific protein phosphatase known to be involvedin the regulation of a variety of cellular processes, such as celldivision, glycogen metabolism, muscle contractility, proteinsynthesis, and HIV-1 viral transcription. Mouse studies suggestthat PP1 functions as a suppressor of learning and memory. Twoalternatively spliced transcript variants encoding distinctisoforms have been observed.
Bio References: Lee, J.H., et al. J. Biol. Chem. 285(32):24466-24476(2010)Fujiki, R., et al. Nature 459(7245):455-459(2009)Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009)Sueyoshi, T., et al. Mol. Pharmacol. 73(4):1113-1121(2008)Rikova, K., et al. Cell 131(6):1190-1203(2007)
Primary Accession: P62140
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP13874b was selected from the C-term region of PPP1CB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.