Biotinylated Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Complex Protein (Monomer, MALS verified)

DESCRIPTION

Human papillomavirus (HPV) is A kind of papillomavirus belonging to the milk polypoid virus family. It is a spherical DNA virus, which can cause the proliferation of squamous epithelium of human skin mucosa. HPV(human papillomavirus) for common warts, genital warts (condyloma acuminatum), and other symptoms. There are many types of human papillomavirus (HPV), with HPV 16 and 18 being high-risk types known to significantly increase the risk of cervical, vaginal and vulvar cancers in women and men. The human HLA-A*0201 HPV (YMLDLQPET) tetramer protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and YMLDLQPET peptide of the HPV.

DETAILS

Tag: C-10×His & C-Avi
Host: HEK293
Size: 200ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Biotinylated Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Complex Protein (HLE-H82E6) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & ALYVDSLFFL peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769-1 (B2M) & ALYVDSLFFL).
Storage: -20℃
Category: MABSol® Biotin Labeled Proteins
Molecule: HLA-A*0201 & B2M & PRAME (ALYVDSLFFL)
Conjugate: Biotin-labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & ALYVDSLFFL peptide
Swiss-prot: AAA59606.1 | P61769-1 | ALYVDSLFFL
Package Size: 200ug*1
Characteristics: Biotinylated Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Complex Protein is produced by co-expression of HLA and B2M loaded with PRAME peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 36.3 kDa and 11.7 kDa. The protein migrates as 40-43 kDa and 10 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 36.3 kDa and 11.7 kDa
Shipping Condition: RT
Species Reactivity: Human
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