CAY10677

DESCRIPTION

A cysmethynil analog that inhibits Icmt with an IC50 value of 0.86 μM; demonstrates nearly 10-fold more potent antiproliferative activity than cysmethynil on human breast cancer MDA-MB-231 cells (IC50s = 2.63 vs. 27.4 μM, respectively) and human prostate cancer PC3 cells (IC50s = 2.55 vs. 25.2 μM, respectively)

DETAILS

Inchi: InChI=1S/C25H37N5/c1-4-7-8-9-10-11-14-30-19-22(18-29(5-2)6-3)23-15-20(12-13-24(23)30)21-16-27-25(26)28-17-21/h12-13,15-17,19H,4-11,14,18H2,1-3H3,(H2,26,27,28)
Purity: ≥98%
Raptas: Product Type|Biochemicals|Small Molecule Inhibitors|Methyltransferases||Research Area|Cancer
Smiles: CCN(CC)CC1=CN(CCCCCCCC)C2=CC=C(C3=CN=C(N)N=C3)C=C21
Inchikey: HKAUEDVXIIXVGY-UHFFFAOYSA-N
Cas Number: 1443253-20-0
Formulation: A crystalline solid
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C25H37N5
Formula Weight: 407.6
Shelf Life Days: 730