NDUFS4 Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 4724
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: NDUFS4
Other Names: NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial, Complex I-18 kDa, CI-18 kDa, Complex I-AQDQ, CI-AQDQ, NADH-ubiquinone oxidoreductase 18 kDa subunit, NDUFS4
Availability: 2 weeks
Bio Background: NDUFS4 is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase(Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane.
Bio References: Panelli,D., et.al., Biochimie 90 (10), 1452-1460 (2008)
Primary Accession: O43181
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP6932b was selected from the C-term region of human NDUFS4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.