sc-393322 SAMPLE sc-393322
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V-ATPase D1 (D-4)
Santa Cruz Biotechnology
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DESCRIPTION
mouse monoclonal IgG1; V-ATPase D1 Antibody (D-4) is an IgG1 κ mouse monoclonal V-ATPase D1 antibody (also designated V-ATPase D1 antibody) that detects the V-ATPase D1 protein of mouse, rat and human origin by WB, IP, IF and ELISA. V-ATPase D1 Antibody (D-4) is available as both the non-conjugated anti-V-ATPase D1 antibody form, as well as multiple conjugated forms of anti-V-ATPase D1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Vacuolar-type H+-ATPase (V-ATPase) is a multisubunit enzyme responsible for the acidification of eukaryotic intracellular organelles. V-ATPases pump protons against an electrochemical gradient, while F-ATPases reverse the process, thereby synthesizing ATP. A peripheral V1 domain, which is responsible for ATP hydrolysis, and an integral V0 domain, which is responsible for proton translocation, comprise the V-ATPase complex. Nine subunits (A-H) make up the V1 domain and five subunits (A, D, C, C' and C") make up the V0 domain. V-ATPase D1 (ATPase, H+ transporting, lysosomal, V0 subunit D1), also known as ATP6V0D1, P39, VATX, VMA6, ATP6D or VPATPD, is the D subunit of the V0 domain. Expressed ubiquitously, V-ATPase D1 acts in concert with other V0 subunits to catalytically acidify a variety of intracellular compartments, thereby synthesizing ATP to be used for vacuolar transport.
DETAILS
- Host: mouse
- Type: Primary
- Uniprot: P61421
- Clonality: Monoclonal
- Conjugate: unconjugated
- Applications: WB, IP, IF, ELISA
- Human Gene Id: 9114
- Mouse Gene Id: 11972
- Protein Target: V-ATPase D1
- Human Gene Name: ATP6V0D1
- Mouse Gene Name: Atp6v0d1
- Species Reactivity: mouse, rat, human
PROMOTION TERMS
Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.
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