Skip to Main Content
More Intelligent Procurement, Faster R&D

Go to Main Navigation

sc-393322 SAMPLE sc-393322

Promo Available Scientist.com Supplier

V-ATPase D1 (D-4)

Santa Cruz Biotechnology

DESCRIPTION

mouse monoclonal IgG1; V-ATPase D1 Antibody (D-4) is an IgG1 κ mouse monoclonal V-ATPase D1 antibody (also designated V-ATPase D1 antibody) that detects the V-ATPase D1 protein of mouse, rat and human origin by WB, IP, IF and ELISA. V-ATPase D1 Antibody (D-4) is available as both the non-conjugated anti-V-ATPase D1 antibody form, as well as multiple conjugated forms of anti-V-ATPase D1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Vacuolar-type H+-ATPase (V-ATPase) is a multisubunit enzyme responsible for the acidification of eukaryotic intracellular organelles. V-ATPases pump protons against an electrochemical gradient, while F-ATPases reverse the process, thereby synthesizing ATP. A peripheral V1 domain, which is responsible for ATP hydrolysis, and an integral V0 domain, which is responsible for proton translocation, comprise the V-ATPase complex. Nine subunits (A-H) make up the V1 domain and five subunits (A, D, C, C' and C") make up the V0 domain. V-ATPase D1 (ATPase, H+ transporting, lysosomal, V0 subunit D1), also known as ATP6V0D1, P39, VATX, VMA6, ATP6D or VPATPD, is the D subunit of the V0 domain. Expressed ubiquitously, V-ATPase D1 acts in concert with other V0 subunits to catalytically acidify a variety of intracellular compartments, thereby synthesizing ATP to be used for vacuolar transport.

DETAILS

  • Host: mouse
  • Type: Primary
  • Uniprot: P61421
  • Clonality: Monoclonal
  • Conjugate: unconjugated
  • Applications: WB, IP, IF, ELISA
  • Human Gene Id: 9114
  • Mouse Gene Id: 11972
  • Protein Target: V-ATPase D1
  • Human Gene Name: ATP6V0D1
  • Mouse Gene Name: Atp6v0d1
  • Species Reactivity: mouse, rat, human

PROMOTION TERMS

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.