p70 S6Kbeta Blocking Peptide (N-term)

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 6199
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: RPS6KB2
Other Names: Ribosomal protein S6 kinase beta-2, S6K-beta-2, S6K2, 70 kDa ribosomal protein S6 kinase 2, P70S6K2, p70-S6K 2, S6 kinase-related kinase, SRK, Serine/threonine-protein kinase 14B, p70 ribosomal S6 kinase beta, S6K-beta, p70 S6 kinase beta, p70 S6K-beta, p70 S6KB, p70-beta, RPS6KB2, STK14B
Availability: 2 weeks
Bio Background: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
Bio References: Raught, B., et al., EMBO J. 23(8):1761-1769 (2004). Lekmine, F., et al., Exp. Cell Res. 295(1):173-182 (2004). Shao, J., et al., Cancer Res. 64(1):229-235 (2004). An, W.L., et al., Am. J. Pathol. 163(2):591-607 (2003). Levy, Y., et al., J. Biol. Chem. 278(16):14533-14542 (2003).
Other Accession: Q9Z1M4
Primary Accession: Q9UBS0
Targetspecificity: The synthetic peptide sequence is selected from aa 5-19 of HUMAN RPS6KB2