BP8009d
p70 S6Kbeta Blocking Peptide (N-term)
Abcepta
DETAILS
- Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
- Gene Id: 6199
- Category: Peptides; Blocking Peptides
- Subtitle: Synthetic peptide
- Gene Name: RPS6KB2
- Other Names: Ribosomal protein S6 kinase beta-2, S6K-beta-2, S6K2, 70 kDa ribosomal protein S6 kinase 2, P70S6K2, p70-S6K 2, S6 kinase-related kinase, SRK, Serine/threonine-protein kinase 14B, p70 ribosomal S6 kinase beta, S6K-beta, p70 S6 kinase beta, p70 S6K-beta, p70 S6KB, p70-beta, RPS6KB2, STK14B
- Availability: 2 weeks
- Bio Background: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
- Bio References: Raught, B., et al., EMBO J. 23(8):1761-1769 (2004). Lekmine, F., et al., Exp. Cell Res. 295(1):173-182 (2004). Shao, J., et al., Cancer Res. 64(1):229-235 (2004). An, W.L., et al., Am. J. Pathol. 163(2):591-607 (2003). Levy, Y., et al., J. Biol. Chem. 278(16):14533-14542 (2003).
- Other Accession: Q9Z1M4
- Primary Accession: Q9UBS0
- Targetspecificity: The synthetic peptide sequence is selected from aa 5-19 of HUMAN RPS6KB2