18194
Scientist.com Supplier
CCT128930
Cayman Chemical
DESCRIPTION:
An ATP-competitive inhibitor of Akt2 (IC50 = 6 nM); blocks the phosphorylation of Akt targets, inhibits proliferation of multiple tumor cell lines in vitro, and prevents the growth of human tumor xenografts in mice
DETAILS
- Inchi: InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23)
- Purity: ≥95%
- Raptas: Product Type|Biochemicals|Kinase Inhibitors|PKB/Akt||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Autophagy||Research Area|Cancer|Cell Signaling|PI3K/Akt/mTOR Signaling||Research Area|Cancer|DNA Damage and Repair||Research Area|Cell Biology|Cell Signaling|PI3K/Akt/mTOR Signaling||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking|Autophagy
- Smiles: ClC(C=C1)=CC=C1CC(CC2)(N)CCN2C3=C4C(NC=C4)=NC=N3
- Inchikey: RZIDZIGAXXNODG-UHFFFAOYSA-N
- Cas Number: 885499-61-6
- Formulation: A crystalline solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C18H20ClN5
- Formula Weight: 341.8
- Shelf Life Days: 1460