PARP2 Antibody (C-term) Blocking peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 11546
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: Parp2
Other Names: Poly [ADP-ribose] polymerase 2, PARP-2, mPARP-2, ADP-ribosyltransferase diphtheria toxin-like 2, ARTD2, NAD(+) ADP-ribosyltransferase 2, ADPRT-2, Poly[ADP-ribose] synthase 2, pADPRT-2, Parp2, Adprt2, Adprtl2, Aspartl2
Availability: 2 weeks
Bio Background: Parp2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Bio References: Brunyanszki, A., et al. J. Invest. Dermatol. 130(11):2629-2637(2010)Toller, I.M., et al. Cancer Res. 70(14):5912-5922(2010)Nicolas, L., et al. Oncogene 29(19):2877-2883(2010)Li, X., et al. J. Neurochem. 113(4):1012-1022(2010)Quenet, D., et al. Exp. Cell Res. 315(16):2824-2834(2009)
Primary Accession: O88554