MAGEF1 Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 64110
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: MAGEF1
Other Names: Melanoma-associated antigen F1, MAGE-F1 antigen, MAGEF1
Availability: 2 weeks
Bio Background: Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGE is unknown, may play a role in embryonal development and tumor transformation or aspects of tumor progression.
Bio References: Stone, B., et al., Gene 267(2):173-182 (2001).
Other Accession: NP_071432
Primary Accession: Q9HAY2
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP6179a was selected from the C-term region of human MAGEF1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.