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GHL-H5284-50ug GHL-H5284-500ug

HHV-5 (strain AD169) Glycoprotein H&L, Twin-Strep Tag&His Tag



HHV-5 (strain AD169) Glycoprotein H&L, Twin-Strep Tag&His Tag (GHL-H5284) is expressed from human 293 cells (HEK293). It contains AA Arg 24 - Leu 720 & Val 31 - Arg 278 (Accession # P12824 & P16832).


  • Tag: C-Twin Strep | C-10×His
  • Host: HEK293
  • Size: 50ug
  • Buffer: PBS, pH7.4
  • Format: Powder
  • Purity: 90%
  • Storage: -20℃
  • Category: Viral Proteins
  • Molecule: Glycoprotein H&L
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: Human cytomegalovirus (HCMV), a prototypical beta-herpes virus, is a major cause of morbidity and mortality in immunocompromised transplant recipients and congenitally infected fetuses.Different HCMV glycoprotein complexes are capable of meditating entry through interaction with cell-specific receptors on a panel of host cells. The pentamer (gH/gL/UL128/UL130/UL131A) mediates HCMV entry into epithelial, endothelial, and myeloid cells by its binding to neuropilin 2 (Nrp2). The trimer (gH/gL/gO) can mediate infection of all cell types by binding to platelet-derived growth factor-alpha (PDGFRα). Both pentamer and trimer need to interact with the glycoprotein B (gB), the fusogenic protein, to trigger the virus and host cell membrane fusion.
  • Exp Region: Arg 24 - Leu 720 & Val 31 - Arg 278
  • Swiss-prot: P12824,P16832
  • Characteristics: This protein . The protein has a calculated MW of 82.6 kDa & 29.5 kDa. The protein migrates as 30-38 kDa and 90-100 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 82.6 kDa & 29.5 kDa
  • Shipping Condition: RT
  • Species Reactivity: HHV-5
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: