SPD-C5227-100ug SPD-C5227-1mg
SARS-CoV-2 Spike RBD Protein (L452Q, F490S), His Tag (MALS verified)
ACROBiosystems
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DESCRIPTION
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
DETAILS
- Tag: C-10×His
- Host: HEK293
- Size: 1mg
- Buffer: PBS, pH7.4
- Format: Powder
- Purity: 95%
- Source: SARS-CoV-2 Spike RBD, His Tag (SPD-C5227) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (L452Q, F490S)). Mutations L452Q, F490S were identified in the SARS-CoV-2 Lambda variant (Pango lineage: C.37).
- Storage: -20℃
- Category: Viral Proteins
- Molecule: Spike RBD
- Accession: QHD43416.1 (L452Q, F490S)
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Arg 319 - Lys 537
- Package Size: 1mg*1
- Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.5 kDa. The protein migrates as 32-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 26.5 kDa
- Shipping Condition: RT
- Species Reactivity: SARS-CoV-2
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html