ULK3 Antibody (C-term) Blocking peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 25989
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: ULK3
Other Names: Serine/threonine-protein kinase ULK3, Unc-51-like kinase 3, ULK3
Availability: 2 weeks
Bio Background: Serine/threonine protein kinase which enhances GLI1 and GLI2 transcriptional activity and consequently positively regulates GLI-dependent SHH signaling. May exert this function by promoting GLI1 nuclear localization. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently.
Bio References: Maloverjan, A., et al. J. Biol. Chem. 285(39):30079-30090(2010)Takeuchi, F., et al. Circulation 121(21):2302-2309(2010)Maloverjan, A., et al. Exp. Cell Res. 316(4):627-637(2010)Levy, D., et al. Nat. Genet. 41(6):677-687(2009)Kim, D.H., et al. Blood 113(11):2517-2525(2009)
Primary Accession: Q6PHR2
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP13473b was selected from the C-term region of ULK3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.