RSK2 (RPS6KA3) Antibody (S369) Blocking peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 6197
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: RPS6KA3
Other Names: Ribosomal protein S6 kinase alpha-3, S6K-alpha-3, 90 kDa ribosomal protein S6 kinase 3, p90-RSK 3, p90RSK3, Insulin-stimulated protein kinase 1, ISPK-1, MAP kinase-activated protein kinase 1b, MAPK-activated protein kinase 1b, MAPKAP kinase 1b, MAPKAPK-1b, Ribosomal S6 kinase 2, RSK-2, pp90RSK2, RPS6KA3, ISPK1, MAPKAPK1B, RSK2
Availability: 2 weeks
Bio Background: RPS6KA3 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase(MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in the gene for this protein have been associated with Coffin-Lowry syndrome (CLS).
Bio References: Cho,Y.Y., J. Biol. Chem. 282 (11), 8380-8392 (2007)Wissing,J., Mol. Cell Proteomics 6 (3), 537-547 (2007)
Primary Accession: P51812
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP7286b was selected from the S369 region of human RPS6KA3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.