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MCF-H5218-20ug MCF-H5218-50ug MCF-H5218-1mg

Human M-CSF / CSF-1 Protein, premium grade

ACROBiosystems

DESCRIPTION

Human M-CSF Protein, premium grade (MCF-H5218) is expressed from human 293 cells (HEK293). It contains AA Glu 33 - Arg 255 (Accession # P09603-1).

DETAILS

  • Tag: Native
  • Host: HEK293
  • Size: 1mg
  • Buffer: PBS, pH7.4
  • Format: Powder
  • Purity: 95%
  • Storage: -20℃
  • Category: Cytokines&Growth Factors
  • Molecule: M-CSF
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. It is one of the three experimentally described colony-stimulating factors. M-CSF binds to the colony stimulating factor 1 receptor. Macrophage colony-stimulating factor has been shown to interact with PIK3R2. M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. Locally produced M-CSF in the vessel wall contributes to the development and progression of atherosclerosis.
  • Exp Region: Glu 33 - Arg 255
  • Swiss-prot: P09603-1
  • Characteristics: This protein carries no "tag". The protein has a calculated MW of 25.1 kDa. The protein migrates as 35-45 kDa under reducing (R) condition, and 50-58 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 0.01 EU per μg
  • Molecular Weight: 25.1 kDa
  • Shipping Condition: RT
  • Species Reactivity: Human
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html