9002002
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BCATc Inhibitor 2
Cayman Chemical
DESCRIPTION:
A sulfonyl hydrazide that inhibits BCATc (IC50s = 0.81 and 0.2 µM in human and rat, respectively) with 15-fold selectivity over BCATm; blocks calcium influx into neurons (IC50 = 4.8 µM) following inhibition of glutamate uptake and demonstrates neuroprotective efficacy in vivo
DETAILS
- Inchi: InChI=1S/C16H10ClF3N2O4S/c17-10-5-6-12-9(7-10)8-13(26-12)15(23)21-22-27(24,25)14-4-2-1-3-11(14)16(18,19)20/h1-8,22H,(H,21,23)
- Purity: ≥98%
- Raptas: Product Type|Biochemicals|Small Molecule Inhibitors|Amino Acid Turnover||Research Area|Endocrinology & Metabolism||Research Area|Neuroscience|Neurodegenerative Disorders
- Smiles: ClC1=CC=C2C(C=C(C(NNS(C3=C(C(F)(F)F)C=CC=C3)(=O)=O)=O)O2)=C1
- Inchikey: ZLQBZYKAQQWOTK-UHFFFAOYSA-N
- Cas Number: 406191-34-2
- Formulation: A crystalline solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C16H10ClF3N2O4S
- Formula Weight: 418.8
- Shelf Life Days: 730