Human IL-7 R alpha / CD127 Protein (I66T, V138I), Mouse IgG2a Fc Tag

DESCRIPTION

Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.

DETAILS

Tag: C-mFc(mIgG2a)
Host: HEK293
Size: 100ug
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
Format: Powder
Purity: 90%
Source: Human IL-7 R alpha, Mouse IgG2a Fc Tag (IL7-H5258) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Gly 236 (Accession # P16871-1 (I66T,V138I)).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: IL-7 R alpha
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Glu 21 - Gly 236
Swiss-prot: P16871-1 (I66T,V138I)
Package Size: 100ug*1
Characteristics: This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 52.0 kDa. The protein migrates as 65-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 52.0 kDa
Shipping Condition: RT
Species Reactivity: Human
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