SCYL2 Antibody(C-term) Blocking peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 55681
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: SCYL2
Other Names: SCY1-like protein 2, Coated vesicle-associated kinase of 104 kDa, SCYL2, CVAK104, KIAA1360
Availability: 2 weeks
Bio Background: SCYL2 is a component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. SCYL2 is a probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine. SCYL2 may also regulate clathrin-dependent trafficking between the TGN and/or the endosomal system.
Bio References: Ota, T., et al., Nat. Genet. 36(1):40-45 (2004).
Primary Accession: Q6P3W7
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP7024b was selected from the C-term region of human SCYL2 (C-term). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.