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RO1-HP2E3-25tests RO1-HP2E3-200tests

PE-Labeled Human ROR1 Protein, His Tag (Site-specific conjugation)

ACROBiosystems

DESCRIPTION

PE-Labeled Human ROR1, His Tag (RO1-HP2E3) is produced via site-specific conjugation of PE to Human ROR1 (30-403), His Tag under optimal conditions with a proprietary technology. Human ROR1, His Tag (RO1-HP2E3) is expressed from human 293 cells (HEK293). It contains AA Gln 30 - Glu 403 (Accession # Q01973-1).

DETAILS

  • Tag: C-10×His
  • Host: HEK293
  • Size: 25tests
  • Buffer: PBS, 0.5% BSA, pH7.4
  • Format: Powder
  • Storage: -20℃, aviod light
  • Category: Fluorescent labeled protein
  • Molecule: ROR1
  • Accession: NP_005003.2
  • Conjugate: PE Labeled
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: Tyrosine-protein kinase transmembrane receptor ROR1 is also known as Neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), which belongs to the protein kinase superfamily or tyr protein kinase family or ROR subfamily. ROR1 contains 1 FZ (frizzled) domain, 1 Ig-like C2-type (immunoglobulin-like) domain, 1 kringle domain, 1 protein kinase domain. ROR1 is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. ROR1 could interact with casein kinase 1 epsilon (CK1ε) to activate phosphoinositide 3-kinase-mediated AKT phosphorylation and cAMP-response-element-binding protein (CREB), which was associated with enhanced tumor-cell growth.
  • Exp Region: Gln 30 - Glu 403
  • Swiss-prot: Q01973-1
  • Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 45.6 kDa.
  • Molecular Weight: 45.6 kDa
  • Shipping Condition: RT
  • Species Reactivity: Human
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html