Human Mucin-1 / MUC-1 (24-380) Protein, His Tag (MALS verified)

DESCRIPTION

Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 100ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 95%
Source: Human Mucin-1 (24-380) Protein, His Tag (MU1-H52H7) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Ser 380 (Accession # P15941-1).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: Mucin-1
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ser 24 - Ser 380
Swiss-prot: P15941-1
Package Size: 100ug*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 35.6 kDa. The protein migrates as 55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 35.6 kDa
Shipping Condition: RT
Species Reactivity: Human
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