GMPR Antibody (N-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 2766
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: GMPR
Other Names: GMP reductase 1, Guanosine 5'-monophosphate oxidoreductase 1, Guanosine monophosphate reductase 1, GMPR, GMPR1
Availability: 2 weeks
Bio Background: Guanosine monophosphate reductase (EC 1.7.1.7) catalyzes the irreversible NADPH-dependent reductive deamination of guanosine monophosphate (GMP) to inosine monophosphate (IMP). GMPR is able to convert guanosine nucleotides to the pivotal precursor of both guanine (G) and adenine (A) nucleotides. It plays an important role in maintaining the intracellular balance of A and G nucleotides.
Bio References: Deng,Y., Int. J. Biochem. Cell Biol. 34 (9), 1035-1050 (2002)Salvatore,D., J. Biol. Chem. 273 (47), 31092-31096 (1998)
Primary Accession: P36959
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP7386a was selected from the N-term region of human GMPR. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.