Human IgG3 Fc Protein, Tag Free (MALS & SPR verified)

DESCRIPTION

Immunoglobulin G3 (IgG3) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-3 chain C region (IgG3-Fc / IGHG3) contains two constant regions of IgG3 H chain (CH2, CH3).

DETAILS

Tag: Native
Host: HEK293
Size: 1mg
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
Format: Powder
Purity: 95%
Source: Human IgG3 Fc, Tag Free (IG3-H5200) is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 377 (Accession # P01860).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: IgG3 Fc
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Glu 99 - Lys 377
Swiss-prot: P01860
Package Size: 500ug*2
Characteristics: This protein carries no "tag". The protein has a calculated MW of 31.2 kDa. The protein migrates as 35-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 31.2 kDa
Shipping Condition: RT
Species Reactivity: Human
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