NAT1 Antibody (center) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 9
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: NAT1
Other Names: Arylamine N-acetyltransferase 1, Arylamide acetylase 1, Monomorphic arylamine N-acetyltransferase, MNAT, N-acetyltransferase type 1, NAT-1, NAT1, AAC1
Availability: 2 weeks
Bio Background: This gene is one of two arylamine N-acetyltransferase(NAT) genes in the human geneome, and is orthologous to the mouseand rat Nat2 genes. The enzyme encoded by this gene catalyzes thetransfer of an acetyl group from acetyl-CoA to various arylamineand hydrazine substrates. This enzyme helps metabolize drugs andother xenobiotics, and functions in folate catabolism. Multipletranscript variants encoding different isoforms have been found forthis gene.
Bio References: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Minchin, R.F., et al. Int. J. Biochem. Cell Biol. 39(11):1999-2005(2007)Barker, D.F., et al. Pharmacogenet. Genomics 16(7):515-525(2006)Boukouvala, S., et al. Basic Clin. Pharmacol. Toxicol. 96(5):343-351(2005)
Primary Accession: P18440
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP13168c was selected from the center region of NAT1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.