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LIT-C5244-100ug LIT-C5244-1mg

Cynomolgus LIGHT / TNFSF14 Protein, His Tag, active trimer (MALS verified)

ACROBiosystems

DESCRIPTION

Tumor necrosis factor ligand superfamily member 14(LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that regulates T cell immune responses by signaling through the herpes virus entry mediator (HVEM) and the lymphotoxin beta receptor (LTbetaR). LIGHT has emerged as a potent initiator of T cell co-stimulation signals effecting CTL-mediated tumor rejection, allograft rejection and graft versus host disease. Constitutive expression of LIGHT leads to tissue destruction and autoimmune-like disease syndromes.

DETAILS

  • Tag: N-10×His
  • Host: HEK293
  • Size: 1mg
  • Buffer: PBS, pH7.4
  • Format: Powder
  • Purity: 90%
  • Source: Cynomolgus LIGHT Protein, His Tag (LIT-C5244) is expressed from human 293 cells (HEK293). It contains AA Asp 74 - Val 240 (Accession # E9NVF7).
  • Storage: -20℃
  • Category: Immune Checkpoint Proteins
  • Molecule: LIGHT
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Exp Region: Asp 74 - Val 240
  • Swiss-prot: E9NVF7
  • Package Size: 500ug*2
  • Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 58.6 kDa. The protein migrates as 63-66 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 58.6 kDa
  • Shipping Condition: RT
  • Species Reactivity: Cynomolgus
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html