FITC-Labeled Human CD27 Ligand / CD70 Protein, His,Flag Tag, active trimer (MALS verified)

DESCRIPTION

Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNγ production, on NK cells.

DETAILS

Tag: N-6×His & N-Flag
Host: HEK293
Size: 25ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: FITC-Labeled Human CD27 Ligand, His,Flag Tag (CDD-HF2D4) is expressed from human 293 cells (HEK293). It contains AA Ser 52 - Pro 193 (Accession # P32970-1). It is the biotinylated form of Human CD27 Ligand, His,Flag Tag (active trimer) (MALS verified) (Cat. No.CDL-H52Da).
Storage: -20℃, aviod light
Category: Fluorescent labeled protein
Molecule: CD27 Ligand
Accession: NP_001243.1
Conjugate: FITC Labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ser 52 - Pro 193
Swiss-prot: P32970-1
Package Size: 25ug*1
Characteristics: This protein carries a polyhistidine tag at the N-terminus, followed by a flag tag. The protein has a calculated MW of 49.3 kDa. The protein migrates as 50-55 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 49.3 kDa
Shipping Condition: RT
Species Reactivity: Human
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