DESCRIPTION

• Tag: C-10×His
• Host: HEK293
• Size: 100ug
• Buffer: PBS, pH7.4
• Format: Powder
• Purity: 85%
• Storage: -20℃
• Category: Bio-Markers & CD Antigens
• Molecule: Glypican 3
• Accession: XP_005594665.1
• Conjugate: Unconjugated
• Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Background: Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
• Exp Region: Gln 25 - His 559
• Characteristics: This protein carries a polyhistidine tag at the C-terminus. This protein contains a furin-like convertase cleavage site, 355-RQYR-358, and will be processed into N and C-terminal fragment with calculated MW of 38.1 kDa and 24.6 kDa respectively. The N and C‑terminal fragment as 42 kDa and 66-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Endotoxin Level: 1.0 EU per μg
• Molecular Weight: 38.1 kDa and 24.6 kDa
• Shipping Condition: RT
• Species Reactivity: Cynomolgus
• Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html